Opioid receptors blockade modulates apoptosis in a rat model of cirrhotic cardiomyopathy
نویسندگان
چکیده
منابع مشابه
Opioid Receptors Blockade Modulates Apoptosis in a Rat Model of Cirrhotic Cardiomyopathy
BACKGROUND Cirrhosis is a common consequence of chronic liver inflammation is known to be associated with various manifestation of cardiovascular dysfunction, which has been introduced as a cirrhotic cardiomyopathy. Some possible pathogenic mechanisms has been reported and still more details should be explored. AIM The present study is the first study to explore the contribution of endogenous...
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Objective(s): An increase in nitric oxide (NO) production has been reported in cirrhotic cardiomyopathy and, portal hypertension. Since minocycline has been shown to inhibit NO overproduction, we aimed to examine its role in a rat model of CCl4-induced cirrhotic cardiovascular complications. Materials and Methods: Portal pressure and inotropic responsiveness of isolated papillary muscles to is...
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متن کاملminocycline attenuates cirrhotic cardiomyopathy and portal hypertension in a rat model: possible involvement of nitric oxide pathway
objective(s): an increase in nitric oxide (no) production has been reported in cirrhotic cardiomyopathy and, portal hypertension. since minocycline has been shown to inhibit no overproduction, we aimed to examine its role in a rat model of ccl4-induced cirrhotic cardiovascular complications. materials and methods: portal pressure and inotropic responsiveness of isolated papillary muscles to iso...
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ژورنال
عنوان ژورنال: Annals of Medical and Health Sciences Research
سال: 2014
ISSN: 2141-9248
DOI: 10.4103/2141-9248.133468